BIOL 3113 Lecture Notes - Lecture 4: Citric Acid Cycle, Atp Hydrolysis, Gastrointestinal Tract
Document Summary
Macromolecules are made from subunits that are linked together in a condensation reaction. Reducing power supplied by electrons donated by nadph. *driven by electron transport across the inner mitochondrial membrane. Hydrolysis = reverse of the dehydration reaction used to attach the subunits together: Digestive tract (multicellular organisms), digestive compartments (within cells) Produced by the repeated addition of a subunit onto one end of a growing chain. Mechanism used to link atp hydrolysis to the monomer addition in condensation reactions in polymer synthesis in cells is very complex and involves: Atp adp + pi (~ 11-13 kcal/mole) Atp amp + ppi + h2o 2 pi (~ 26 kcal/mole) or. 2atp nucleoside monophospate nucleoside trisphospate when added to the chain ppi released. Enzymes responsible for the reactions of metabolism are not randomly distributed in cell. Cells use various strategies to organize enzymes to increase their efficiency: