BIO 110 Lecture Notes - Lecture 23: Pyruvate Decarboxylase, Lactate Dehydrogenase, Alcohol Dehydrogenase

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22 Nov 2016
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Three steps have very large negative g"s are thus essentially irreversible (steps. Needs oxygen to go from pyruvate to acetyl-coa. Fermentation - taking electrons from nadh and transfer to pyruvate forms lactate. 2 steps (rather than 1 step like lactate) Pyruvate decarboxylase - removing a carbon to form co2. In muscle (glycolysis) - glucose pyruvate (2 phosphates) lactate . In liver (gluconeogenesis) - lactate (nadh is generated) pyruvate (6. Phosphatase) glucose sent into blood muscle (stored or used) Creates an environment in which certain microbes can grow, but not ones that are harmful or make food taste bad. Put into salt solution deprive of oxygen. Lack of oxygen microbes start growing lactate and alcohols start building up (inhospitable for most bacteria) lowers ph and increases alcohol concentration. Catabolism - breakdown of large molecules into smaller molecules. Anabolism - building of large molecules from smaller molecules. Citric acid cycle - electrons move from one metabolic pathway to another.

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