BIOC 406 Lecture Notes - Lecture 11: Pyrimidine, Purine, Nucleobase
Document Summary
Nucleotides --more than precursors for rna and dna. Gtp: high energy; control protein camp: downstream response of g-protein coupled receptors. Ribose ring: a ve-membered ring with three hydroxyls; carbons numbered 1"-5", with the 5" carbon being the one outside the ring. They are numbered prime because they must be disgnguished from the nucleo-base being added later on (purine/pyrimidine). 2"-deoxyr-ribose-5"-phosphate: has been reduced at the 2 posigon so that you have a proton instead of a hydroxyl. This is ulgmately the main di erence between rna and dna. The presence of the 2" hydroxyl has funcgonal di erences. Purines: heterocyclic, two rings: one six membered and one ve membered. This forms the basis of synthesizing the two most important purines: adenine and guanine. Pyrimidines: six-membered cyclic ring numbered 1-6; thymine, which is mostly found in dna; uracil, mostly found in rna, cytosine, found in either one.
