PSYCH 202 Lecture Notes - Lecture 42: Psilocybin, Stimulant, Basal Ganglia
22 Mar 2018
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Document Summary
Outline: psychoactive drugs (what are they, mechanisms of action: at the synapse, primary influences of (some) recreational drugs. Psychoactive drug: a chemical substance that alters perceptions and/or mood (affects consciousness, marijuana, ecstasy, heroin, caffeine, alcohol, chocolate. Influence nt systems: many ways to influence nt functioning explicitly at the synapse. Drugs interfere with nt functioning: presynaptic effects, nt production. Inhibition of transmitter synthesis: blockade of axonal transport. Interference with the storage of transmitters: nt release, prevention of synaptic transmission, alteration of synaptic transmitter release, modulation of transmitter release by presynaptic receptors, nt clearance (e. g. reuptake. Inactivation of transmitter reuptake: blockade of transmitter degradation, postsynaptic effects, receptor, effects on transmitter receptors, blockade of receptors, activation of receptors, other cell processes, effects on cellular processes, alteration of the number of postsynaptic receptors. Antagonists decrease nt effects: agonist/antagonist does not tell us about excitability effects, need to know which nt, and sometimes, the receptor type.
