MCB 10 Lecture Notes - Lecture 9: Intron, Heritability, Twin

• School: UC-Davis
• Department: Molecular and Cellular Biology
• Course: MCB 10
• Professor: Rannala Bruce

Document Summary

Translation: process of reading the mrna base sequence and creating the amino acid sequence of a protein, occurs on the ribosome. The genetic code: correspondence between the chemical languages of mrna and proteins. In the 1960s, researchers used logic and experiments with synthetic rnas to decipher the genetic code: more recently, annotations of the human genome has confirmed and extended the earlier work. Three successive mrna bases form a codon: there are 64 codons. Human genome sequence: orientation: d(cid:374)a se(cid:395)ue(cid:374)ces a(cid:396)e o(cid:396)ie(cid:374)ted f(cid:396)o(cid:373) 5" to 3", ge(cid:374)o(cid:373)e se(cid:395)ue(cid:374)ces a(cid:396)e o(cid:396)ie(cid:374)ted f(cid:396)o(cid:373) sho(cid:396)t p a(cid:396)(cid:373) to lo(cid:374)g (cid:395) a(cid:396)(cid:373) a(cid:374)d i(cid:374) a 5" to 3" direction. Control of gene expression: protein encoding gene contains some controls over its own expression level. Extra copies of gene: much of the control of gene expression occurs in 2 general processes. Chromatin remodeling: histones play major role in gene expression.