MIC 102 Lecture Notes - Lecture 14: Chemoreceptor, Signal Transduction, Sigma Factor
Document Summary
Starvation specific nutrient limitation, general starvation. Similar responses to stress: sense the stressor, respond to stressor, turn off response when stressor is gone. Response is typically carried out by: protein sensor, transmitted signal that affects gene expression, feedback control mechanism. Signal transduction: signals are converted from one form into another sequentially. Response regulator can do many things besides dna binding, but that is most common. Can also be in stress response but also other reason. Chaperone phou connects phor to pi transporter. No pi -> no phou alters conformation, allows phor to autophosphorylate and then phosphorylates phob. Sensor is actually a sigma factor mrna: heat stress causes hairpin to melt opening mrna sd sequence for translation, rpoh favors rnap binding and expression of heat response genes, dnak chaperone/ftsh protease control of this process. Many ways to get to stationary phase.
