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NPB 10 Lecture Notes - Lecture 17: Oogenesis, Jejunum, Zygote

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School
UC-Davis
Department
Neurobiology,Physio & Behavior
Course
NPB 10
Professor
Erwin Bautista

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Document Summary

Luteal phase: follicular phase follicle grows and follicle secretes estrogen. Myometrium: outermost layer; tissue that surrounds the organ. Proliferation of endometrium: promoted by estrogen (from the ovarian follicle). Secretory phase: endometrium stops growing, secreting fuel called glycogen, mucus, promoted by progesterone and maintained by estrogen. Pregnan(cid:272)y doesn"t o(cid:272)(cid:272)ur c. l. starts to degenerate estrogen and progesterone levels begin to fall. Ovulation: occurring during about 14 days into the follicular cycle, caused by a dramatic increase in anterior pituitary hormone lh, lh-surge, normally estrogen does negative feedback on lh secretion, hypothalamus gnrh (+) ant. Pituitary lh and fsh (+) ovary estrogen female secondary characteristics, oogenesis, uterine cycle: estrogen negatively feedbacks to the ant. pit. The negative feedback is occurring about 0-13 days of follicular cycle. Lh surge is the signal that (cid:272)auses ovulation. Won"t get that signal if the estrogen levels are low. Have to be high enough to do the positive feedback.

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Related Questions

Terms: 1, 14, 28, corpus luteum, estradiol, follicular,GnRH, inhibitory, LH surge, luteal, ovulatory, progesterone,regresses, stimulatory

The ovarian cycle refers to the recurrent, cyclic changes inhormone secretion and follicle/oocyte development that occurroughly every 28 days in the 'typical' woman. The ovarian cycle canbroadly be divided into 3 sequential phases, the first, or_____________ phase which precedes or comes before release of theegg, the middle or ____________ phase during which the egg isactually released, and the final or _______________ phase whichcomes after the egg is released and lasts until the next cyclebegins.

Day 1 of the follicular phase marks the beginning of a newcycle. During the follicular phase, as the name implies, a 'cohort'or small group of follicles (i.e. the structures in the ovary inwhich the oocytes are maturing) begin to grow, develop and preparetheir oocytes for release in response to FSH stimulation from theanterior pituitary. These follicles are the main hormone-secretingstructures in the ovary and the main hormone they are secreting is____________. Early in the phase, when estrogen levels are low, theestrogen exerts ____________feedback control on thehypothalamic-pituitary axis and keep GnRH, LH and FSH levelsrelatively low. Eventually, a single follicle assumes dominance,outgrows and out develops the others, and begins to secrete largerand larger amounts of estrogen. When estrogen levels becomesufficiently high, estrogen's effect at the hypothalamus becomestransiently ______________, causing increases in GnRH secretionthat trigger a mid-cycle _______________.

Right around mid-cycle or around day _________ of the 'typical'__________ day long cycle, under the influence of high levels of LHproduced by the LH surge, the wall of the dominant follicle thinsand eventually ruptures, releasing the egg. This release of the eggis termed ovulation, hence the portion of the cycle immediatelypreceding and including ovulation is termed the ovulatory phase.Another effect of LH is that it luteinizes the follicle, producingchanges in the follicle cells that enable the granulosa cells tosecrete ____________ in addition to estratiol.

The final phase of the ovarian cycle, the luteal phase, beginsimmediately after ovulation and lasts until day 1 of the nextcycle. The luteal phase is characterize by the presence andfunctioning of a _____________. This is the name for the structurethat develops from the follicle after it has lost its egg. Theremainder of the follicle involutes or falls in upon itself,becomes highly vascularized and its luteinized' cells secrete highconcentrations of progesterone in addition to estradiol. Theprogesterone exerts an overriding inhibitory effect on hypothalamic__________ secretion at this time. In the absence of pregnancy, theCL will remain highly active for ~12 days before it __________, orbegins to die off and cease its hormone-secreting activities. CLregression causes a rapid drop in the concentrations of estrogenand progesterone secretion over the next 2 days that will result inshedding of the endometrial lining of the uterus and menstruation.Day 1 of menstruation coincides with and serves as the externalindicator that day _________ of a new ovarian cycle has begun.

Please briefly explain reasoning for all questions.

1)

Which of the following is a component of a vertebrate kidney? (Select all correct choices.)
glomerulus
Bowman's capsule
renal tubules
collecting ducts
Malphigian tubules

2)

In organisms, the ability to control osmosis depends on the properties of the plasma membranes of individual cells. Based on their ability to permit the free movement of water and some solutes, these membranes are best described as: (select all correct choices)
impermeable.
permeable.
semipermeable.
diffusible.
impervious.

3)

True or false: The inner cell mass of the blastocyst becomes the embryo, while the outer cell layer of the blastocyst forms part of the placenta.
true
false

4)

Which of the following accurately characterizes the early cleavage divisions in most animals, although not necessarily in mammals?
They do not involve an increase in the size of the zygote.
They are directed by the zygote’s genome.
They are relatively slow.
They do not occur at the same time, so at any given moment the zygote may have an odd number of cells.
All of these choices are correct.

5)

A key difference between hormonal regulation of the reproductive systems of males and females is that:
LH and FSH are released only in females.
LH and FSH are released only in males.
LH and FSH are released cyclically in females but nearly continuously in males.
LH is released in males and FSH is released in females.
LH is released continuously in males and FSH is released cyclically in females.

6)

Compared to sexual reproduction, asexual reproduction: (select all correct choices)
requires less investment in attracting mates.
allows much more rapid population growth.
is rarely found as the sole mechanism of reproduction.
results in the production of genetically identical cells or individuals.
involves meiosis and fertilization as core processes.

7)

True or false: In response to LH and FSH, ovaries secrete estrogen and progesterone.
true
false

8)

During the luteal phase of the menstrual cycle, if the oocyte is not fertilized, a number of events occur which are listed below. Select the answer that places the events in the correct chronological order.

Events:
1. the lining of the uterus is shed
2. the corpus luteum secretes progesterone
3. follicle cells are converted to the corpus luteum
4. the corpus luteum degenerates
5. estrogen and progesterone levels fall

3, 2, 4, 5, 1

1, 2, 3, 4, 5

2, 4, 3, 1, 5

4, 3, 2, 1, 5
5, 2, 3, 4, 1

9)

If an antibody is missing its Fc fragment, what would happen if this antibody encounters its target antigen in the bloodstream? Select all correct choices.
The antibody would be able to bind the antigen at a specific epitope.
The antibody would be able to bind the antigen, but not at an epitope site.
The antibody would not be able to bind to the antigen.
The antibody would be able to activate components of the complement system.
The antibody would not be able to activate components of the complement system.

10)

If an individual carries a mutation that results in a complete lack of MHC class I proteins, how would the individual’s immune response be affected? Select all correct choices.
Memory cell antibodies would not be able to attach to antigen epitopes.
Cytotoxic T cells would not be able to target (and destroy) infected cells.
Helper T cells would not be able to interact with antigen-presenting cells.
Plasma cell antibodies would not be able to attach to antigen epitopes.

11)

If an individual carries a mutation that results in a complete lack of MHC class I proteins, how would the individual’s immune response be affected? Select all correct choices.
Memory cell antibodies would not be able to attach to antigen epitopes.
Cytotoxic T cells would not be able to target (and destroy) infected cells.
Helper T cells would not be able to interact with antigen-presenting cells.
Plasma cell antibodies would not be able to attach to antigen epitopes.

12)

Which of the following statements is true regarding T cell receptors? Select all correct choices.
They recognize antigen-MHC complexes.
They contain variable and constant regions.
They are composed of two heavy (H) chains and two light (L) chains.
They are formed by the rearrangement of V, J, C, and D gene segments.
They can be found in the bloodstream independent of T cells.