NPB 101 Lecture Notes - Lecture 38: Pituitary Gland, Endocrine Disease, Circulatory System

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Hypothalamus is the site in out cns that collects and integrates information from different inputs. Pituitary is the master endocrine gland that controls many of the endocrine systems in our body. Tropic anterior pituitary are controlled by hypothalamic releasing or inhibiting hormones. Secretion of each anterior pituitary hormone is stimulated or inhibited by one or more hypothalamic hypophysiotropic hormones. Very low amounts detectable in systemic circulation. Features of hypothalamic-pituitary endocrine axis" control: the activity of a specific axis is normally maintained at a set point" which varies from individual-individual within a normal range. If level of a peripheral hormone drops below this set point, secret ion of hypothalamic releasing hormones and/or pituitary tropic hormones will increase. If level of a peripheral hormone rises above this set point, secretion of releasing and tropic hormones will decrease. Features of hypothalamic-pituitary endocrine axis" control: hypothalamic hypophysiotropic neurons receive numerous inputs from higher and lower levels of the brain.

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