NPB 101 Lecture Notes - Lecture 42: Natural Killer Cell, Humoral Immunity, Monocyte

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burgundywombat446

28 Nov 2017

School

UC-Davis

Department

Neurobiology,Physio & Behavior

Course

NPB 101

Professor

Fuller Charles

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Document Summary

The cells that make up the immune system. Collective name for all the immune cells in our body. Myeloid cells (monocytes/macrophages, granulocytes and precursors for red blood cells and platelets. The cells that make up the immune system -- t lymphocytes (t cells) Scavenge our tissues in search of pathogens, dead cells and other debris. Professional phagocytic cells that release the content of their granular as part of specific immune responses (e. g. against large extracellular parasites) A b cell makes only kind of 1 antibody. Each antibody is highly specific for one particular antigen (usually a part of a protein) Problem: there is an near-infinite number of antigens that we could possibly encounter during our lifetime. How can a single b cell make a difference against a pathogen. Activation of complment pathway, a cascade of biochemical response that ends with the formation of membrane attack complex which kills pathogens.

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_______Column A___________________ ___________________Column B_____________________

_____ Glial Cells 1. Can be used to treat follicular B-cell lymphoma; Antibody to Fab Region

___ Helper T-Cells 2. Interspersed among columnar ciliated epithelial cells; contain macrophages

____ Avidin 3. Primary lymphoid organ

____ CD20 on B-cell leukemia 4. Ricin replacing Fc region in an anti-cancer antibody

____ Myeloid Series Cell 5. co-stimulatory molecule on APC. Binds to CD28

___ CD34 6. Can bind circulating leucocytes to endothelial linings

___ M-Cells and MALT 7. Coded for by Variable region genes and diversification and joining region genes

____ B7 8. Macrophage-like cell in the brain

____ Stromal cell 9. Isotype activating basophils and mast cells

____ Thymus 10. Macrophages in the brain

__ Erythropoetin 11. Supporting tissue for example in bone marrow

___ Heavy chain Fab Regions 12. Uses mouse CDRâs and human Fc

___ Immunotoxin 13. Hematopoietic Stem Cell Marker

____ Autologous 14. Use CD4 co-receptors and IL1 receptors to interact with activated macrophages

____ Megacaryocytes and platelets 15. Secondary lymphoid organ

____ CAM 16. Stimulates Red Blood Cell production

___ Myeloma Cell 17. From the patient her/him self

__ Humanized mouse monoclonal antibody 18. Target for Rituxin

____ Anti-idiotype antibody 19. Neutrophil

____ Cervical lymph node 20. Control blood clotting

___ Cytokines and chemokines 21. Getting out of the blood stream

____ extravasation 22. Dendritic cells in the skin

____ Langerhans cells 23. Is immortal

_____ IgE 24. Has high affinity for biotin

____ Osteoclasts 25. Signal molecules released from granules

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11. Which type of immunityoccurs as a response to illness or vaccination?

	Acquired active
	Acquired passive
	Natural

12. What are the uniquecharacteristics of the immune system?

	repository, recognition, defense
	self recognition, specificity, memory
	interception, defense, notification
	specificity, memory, defense

13. Which of the followingis not one of the three unique characteristics ofthe immune system?

	memory
	sensitivity
	specificity
	self-recognition

14. Which of the followingis an age related change associated with the immune system?

	Increase in the number of macrophages and monocytes
	The thymus continues to produce the same number of T cells withage
	The rate of B-cell production declines with age
	Immune memory declines with aging

15. A decrease in ________secretion causes a lowering of blood volume and blood pressure andan increase is body osmotic pressure.

	FSH
	GH
	LDH
	T3
	ADH

16. Which of the followingstatements regarding antibodies is true?

	they destroy antigens by engulfing them
	IgA activates the complement system
	IgE antibodies release histamine and cause inflammation
	Antibodies are manufacture and by platelets

17. Which condition causesautoimmune damage to receptors for acetylcholine at theneuromuscular junction?

	Multiple sclerosis
	Rheumatoid arthritis
	Myasthenia gravis
	Crohn's disease

18. Which is true inregards to Immune memory?

	the number of memory cells increase with age due to the fact thebody has been exposed to numerous antigens throughout life
	the strength of the memory cells is not altered with aging butthe speed in which the memory cells responds decreases with age
	the function of the memory cells is not really altered until thepatient reaches approximately eighty years of age
	less decline in the ability to maintain memory that was producedduring youth or young adulthood, as oppose to memory that came onin older adulthood

19. All of the followingare ways to minimize the undesirable effects of aging on our immunesystem, except what?

	diet low in complex carbs
	regular vaccinations
	seek early treatment when ill
	wearing sun protection

20. Which type of immunesystem cell is formed from an unspecialized lymphocyte because ofthe influence of the thymus on the lymphocyte?

	A-Cell
	D-Cell
	G-Cell
	M-Cell
	T-Cell

11. Which condition causes autoimmune damage toreceptors for acetylcholine at the neuromuscular junction?

	Multiple sclerosis
	Rheumatoid arthritis
	Myasthenia gravis
	Crohn's disease

12. Which is true in regards to Immune memory?

	the number of memory cells increase with age due to the factthe body has been exposed to numerous antigens throughout life
	the strength of the memory cells is not altered with aging butthe speed in which the memory cells responds decreases withage
	the function of the memory cells is not really altered untilthe patient reaches approximately eighty years of age
	less decline in the ability to maintain memory that wasproduced during youth or young adulthood, as oppose to memory thatcame on in older adulthood

13. Which type of immunity occurs as a response toillness or vaccination?

	Acquired active
	Acquired passive
	Natural

14. A decrease in ________ secretion causes alowering of blood volume and blood pressure and an increase is bodyosmotic pressure.

	FSH
	GH
	LDH
	T3
	ADH

15. Which of the following is notone of the three unique characteristics of the immune system?

	memory
	sensitivity
	specificity
	self-recognition

16. Which of the following is an age related changeassociated with the immune system?

	Increase in the number of macrophages and monocytes
	The thymus continues to produce the same number of T cells withage
	The rate of B-cell production declines with age
	Immune memory declines with aging

17. All of the following are ways to minimize theundesirable effects of aging on our immune system, except what?

	diet low in complex carbs
	regular vaccinations
	seek early treatment when ill
	wearing sun protection

18. Which of the following statements regardingantibodies is true?

	they destroy antigens by engulfing them
	IgA activates the complement system
	IgE antibodies release histamine and cause inflammation
	Antibodies are manufacture and by platelets

19. What are the unique characteristics of the immunesystem?

	repository, recognition, defense
	self recognition, specificity, memory
	interception, defense, notification
	specificity, memory, defense

20. Which type of immune system cell is formed froman unspecialized lymphocyte because of the influence of the thymuson the lymphocyte?

	A-Cell
	D-Cell
	G-Cell
	M-Cell
	T-Cell

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NPB 101 Lecture Notes - Lecture 42: Natural Killer Cell, Humoral Immunity, Monocyte

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