NPB 113 Lecture Notes - Lecture 11: Vascular Smooth Muscle, Adrenal Medulla, Polycythemia

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Arteries , arterioles , and capillaries have low compliance. Elastic arteries have higher compliance compared to muscular arteries. " pol seville "s law : resistance = 8met length viscosity l r 4 it. " blood flow = ,{i=dpr8th ( us costly ) determined by : Polycythemia disorder t rbc count t viscosity. To change r ( radius ) contract or relax vascular smooth muscle. Sympathetic input to vsm causes contraction t radius and t resistance. Norepinephrine from postganglionic sns neurons and epinephrine hormone from adrenal medulla released. Parasympathetic input : virtually no effects by pns. Causes vasodilation in salivary glands , gi vasculature . and erectile tissue. " arteriolar vasodilation : allow blood flow to specific vascular beds ( capillaries ) supplying organs 1 tissues. Occurs in response to t metabolism and release of local metabolites. Local metabolites : adenosine , co2 , ht . T ck t] ece active tissue relaxes arteriolar smooth muscle.

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