PSC 101 Lecture Notes - Lecture 14: Foxp2, Developmental Coordination Disorder, Frontal Lobe

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18 Nov 2016
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Psc 101 lecture 14 vocal communication. Verbal dyspraxia: an impaired ability to perform the coordinated movements that are required for speech. In one family (ke), it appears that this disorder is caused by a mutation to the foxp2 gene effects are stronger with articulation of speech rather than comprehension. Language development depends on experience during a sensitive period. A mutation of the foxp2 gene delays learning to speak. The transcriptional factor controls the expression of other genes. Foxp2 gene is very different in humans than in apes, suggesting rapid evolution of this gene. In several species, it is expressed in brain areas associated with vocal learning. Sounds may distinguish species, signal readiness to mate, or alert others to danger. A parallel to humans is that mice with foxp2 mutations have impaired vocalization. Mice vocalizations are ultrasonic ( very high frequency) Genetically identical male mice show individual differences in vocalizations.

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