ANATOMY 201 Lecture Notes - Lecture 10: Ileocecal Valve, Coeliac Disease, Gluten
22 May 2018
School
Department
Course
Professor
Celiac Disease
-An allergy to the gluten protein which is found in grains and wheat.
-If you have an allergy to it it can make you sick
-If you eat a lot of gluten and you have celiac disease, gluten will get to small intestines and it
will cause all the cells in your small intestine to get inflamed.
-Everything Is inflamed, a lot of blood flow in there, increased cell death, buildup of scar tissue
over time
-If you are consistently eating wheat and have gluten allergy, you will damage the wall of your
intestines. The finger projections will go away and it will be a mess
-Losing villi over time will decrease the efficiency of nutrient absorption
Large intestine: Short and fat
Three finger widths in diameter
Has a very specific purpose
Major components first-
• Enter large intestine after you are done going into large intestine through ileocecal
valve, which will close off the opening to your large intestine (opening from ilieum, last
part of small intestine, to opening of secum).
• Cecum is large fat part of large intestine and it is a food collecting area. It will fill in and
sit inside the cecum.
• As food enters into the cecum, it just hangs out there for a while
• The cecum is first area you enter, and then after you leave the ceum, you get to the
ascending colon.
• Right angle turn known as the Right colic flexure
• Transverse colon
• Left colic flexure
• Descending colon runs downwards until you run into S shaped curve called sigmoid
colon
• Get to rectum, holding area for poop
• Anus is where poop leaves your body
Structure
-Diameter of large intestine is bigger
-Haustraum: Weird, little folds on the external and internal surface of the large intestine.
Increase surface area because primary absorption that goes on in large intestine is water and
electrolytes.
- A specific cell that does that is called the colonocyte. Primary cell you see in the walls of the
large intestine.
-Structure will be different.
-In large intestine, you will have a relatively smooth surface
-Because you have hard poop moving through large intestine, the surface is smooth to
accommodate that.
find more resources at oneclass.com
find more resources at oneclass.com
Document Summary
An allergy to the gluten protein which is found in grains and wheat. If you have an allergy to it it can make you sick. If you eat a lot of gluten and you have celiac disease, gluten will get to small intestines and it will cause all the cells in your small intestine to get inflamed. Everything is inflamed, a lot of blood flow in there, increased cell death, buildup of scar tissue over time. If you are consistently eating wheat and have gluten allergy, you will damage the wall of your intestines. The finger projections will go away and it will be a mess. Losing villi over time will decrease the efficiency of nutrient absorption. Haustraum: weird, little folds on the external and internal surface of the large intestine. Increase surface area because primary absorption that goes on in large intestine is water and electrolytes. A specific cell that does that is called the colonocyte.
