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Lecture 27

BIO SCI 93 Lecture Notes - Lecture 27: Heterochromatin, Chromatin, EuchromatinPremium


Department
Biological Sciences
Course Code
BIO SCI 93
Professor
WOOD, M., GREEN, K., BUSCIGLIO, J
Lecture
27

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Biology 93
Gene Expression Regulation
Cell differences are to different gene expression, not because of different genes
Each stage of DNA transcription and translation is potential control point for gene
expression and protein function
Chromatin- made up of DNA and protein; found in nucleus
Histones responsible for DNA packing in first level in chromatin
https://www.quora.com/What-are-the-differences-between-chromosomes-
chromatids-and-chromatin
Chromatin packed loosely in nucleus during interphase; condenses before
mitosis
Loosely packed chromatin= euchromatin
During interphase, centromeres and telomeres condensed into
heterochromatin
Dense packing in heterochromatin= difficult to express genetic info
Transcription Regulation Level
Chromatin- regulates gene expression
Histone tails can be modified through acetylation, which regulates the expression
of genes.
Histone acetylation= acetyl groups attach to + charged lysines in histone tails
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