BIO SCI 37 Lecture Notes - Lecture 16: Blood Vessel, Cardiovascular Disease

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Cns accounts for about 2% of the total body weight. 15% of total blood that the heart pumps to the body s organs and tissues under resting conditions. Cns has a high rate of metabolic activity compared to other tissues, thus it has a high demand for glucose and oxygen. Have to profuse the brain adequately with the brain supply. 20% of all oxygen and 50% of all glucose consumed goes to the brain. Adequate blood flow to the cns must be maintained at all times. Because of bleeding or a blockage- blood is not transported to a specific part of the brain (stroke) Ischemic stroke is a blockage inside a blood vessel. Blockage can be severe or narrow to constrict the flow. Thrombotic- plaque occludes an artery of the carotoid artery. Embolic- plaque or clot breaks off and blocks artery. Penumbra gets larger over time and the dying tissue gets larger.

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