BIO SCI 38 Lecture Notes - Lecture 5: Fear Conditioning, Nmda Receptor, Phosphatase
1 Sep 2016
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Document Summary
What are the four principles of the neuron doctrine as proposed by santiago. Neurons are independent, genetically derived units that have a cell body (soma), dendrite, and axon. Axons could travel distances but terminate at specific locations at dendrites. Electrical activity flows from dendrite to axon. Neurons are the functional units of the nervous system and synapses are their connections. The brain is made of nerve cells with external membranes. There is a strengthened connection between pre and postsynaptic neuron when repeated firing occurs. Synapses are modifiable by experience and this process is central to memory. Extracellular signal binds to cell surface, causing change in conformation of receptor to open channels (activate signaling protein) or transmit info to signaling protein attached to receptor and activate it. Signaling proteins modify function of other proteins. Kinase: add phosphate to turn on or off protein. G-protein: toggle other protein to turn on or off.
