BIO SCI 47 Lecture Notes - Lecture 14: Glucocorticoid, Memory Consolidation, Glutamatergic
11 May 2018
School
Department
Course
Professor
Stress Lecture 14
● LTP makes synapses more sensitive
● LTD desensitizes synapses
● Fight or flight enhances memory
○ Long term glucocorticoid rise inhibits it
● Amygdala sits at the tip of the hippocampus
○ A focus center
■ Fine tuned for fear
○ Amygdala picks up on things before you do
● Amygdala sends signals to hypothalamus and then stress response goes
● Amygdala directly affects memory storage
● Increased amygdala activity heightened memory formation in the hippocampus
● Memory is not solely dependent on amygdala
○ It is dependent on amygdala activating your sympathetic
● Neurons are in networks
● First layer of neurons know one fact of what they do
○ They send messages to second layer in network
○ Projection pattern: 1 talks to A, B, and C; 2 talks to B, C, and D; 3 talks to C, D,
and E
● Neuron C has multiple inputs of information
○ Most neurons in your cortex process memory like neurons B through D, not like A
or E
● Synapses are the tiny gaps between the thready branches of two neurons
Document Summary
Amygdala sits at the tip of the hippocampus. Amygdala picks up on things before you do. Amygdala sends signals to hypothalamus and then stress response goes. Increased amygdala activity heightened memory formation in the hippocampus. Memory is not solely dependent on amygdala. It is dependent on amygdala activating your sympathetic. First layer of neurons know one fact of what they do. They send messages to second layer in network. Projection pattern: 1 talks to a, b, and c; 2 talks to b, c, and d; 3 talks to c, d, and e. Neuron c has multiple inputs of information. Most neurons in your cortex process memory like neurons b through d, not like a or e. Synapses are the tiny gaps between the thready branches of two neurons. When a wave of electrical excitation sweeps over a neuron, this triggers the release of chemical messengers neurotransmitters that float across the synapse and excite the next neuron.
