BIO SCI 75 Lecture Notes - Lecture 8: Klinefelter Syndrome, Sickle-Cell Disease, Turner Syndrome
Document Summary
Human genetic disease re usually caused by mutation in a single gene. Chromosomes errors cause many pregnancies to end before they are even detected: when cells divide sometimes chromosomes don"t wind up where they need to go. Chromosomes are the main carriers of genetic dna. Human chromosomes re in pairs except for sex chromosomes. Xo: no y chromosome and only one x chromosome. Infertile: mostly female males will not survive if they just have a y. If they want to have kids they must use reproductive technologies: most are never diagnosed. Smallest chromosome other than y: most common mutation, more common with an older mother. Pre-sperm cells: result in identical diploid cells(2n=46 chromosomes, meiosis-future, germ cells only, mitosis. Bunch of strings of dna that are doubling. Each half of the chromosomes is a sister chromatid. All chromosomes line up randomly in the center.
