D103 - Lecture 25 - Cytokinesis & Meiosis.docx

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Department
Biological Sciences
Course
BIO SCI D103
Professor
Grant Mac Gregor
Semester
Winter

Description
A. Cytokinesis a. Contractile Ring i. Using actin/myosin filaments ii. Separates cells into two iii. Attaches at the midbody 1. Different posttranslational modifications b. Vesicles fuse with the plasma membrane to allow for the cell to elongate c. Dense Matrix Material i. At the center of the midbody b. Rho A i. GTPase 1. GEF is localized in the midbody ii. Activation of actin filament formation, myosin II activation iii. Activates Formin and Rho Kinase(Rock) B. Meiosis a. Increase genetic diversity i. Leads to higher chance of survival b. Error-prone i. Non-disjunction at Meiosis I 1. Homologous chromosomes don’t separate ii. Meiosis II 1. Sister chromatids don't separate ii. Patau's Syndrome 1. Trisomy 13 b. Chiasmata i. Crossing over points b. S-cyclins are inhibited during meiosis i. No DNA replication b. Prophase I i. Leptotene 1. Thin
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