BIO SCI D104 Lecture Notes - Lecture 5: Big Wing, Homeosis, Ultrabithorax
2 Mar 2014
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D104 lecture 5 review session for midterm exam on jan 21 monday 4-6 pm rm 4201 nat sci ii. Mutual regulation of gap gene expression: one gap gene controlling the expression of another gap gene causes mutually exclusive domains, gap genes control the pair rule genes and the pair rule genes control the segment polarity genes. Mutant phenotypes of pair-rule genes embryo ends up with only 7 parasegments in mutants vs. 14 parasegments in normal embryo focus on even-skipped today. Pair-rule gene expression: which mutation is this : even skipped (purple disappeared, without the dotted lines, it could be krupple. Primary and secondary pair-rule genes pair rule genes controlled by gap genes and also materal effect genes. The eve promoter contains independent regulatory modules for individual stripes yellow regions = regulatory regions/genes to control eve gene distinct regions that control spatial expression in the embryo. Stripe 2 element controls expression in parasegment 3.
