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University of California - Irvine
Biological Sciences
Chuck O' Connell

Chapter 5: Membrane dynamics: useful to think of body in terms of “compartments” -cell membranes separate into two major fluid compartments Fluid body compartments—2 major subdivisions: -intracellular fluid: inside cells; yellow in picture and inside red blood cell; not spatially continuous; a sum of a whole bunch of cell fluids (ICF) -extracellular fluid: outside cells; (ECF) +plasma: inside the blood vessels (red pathway) but outside the red blood cells +interstitial fluid: purple fluid red=capillary Fluid body compartments: differences in chemical composition *be familiar with milli, micro, mega moles conversions -draw charges in the “key” (+,+,-,-) -cations: ions with a positive charge -anions: ions with negative charge -solute: dissolved in the solvent; the key consists of the solutes and the water is the solvent -Intracellular fluid: K+ is primary cation and proteins are primary anions -Interstitual fluid and Plasma: Na+ is primary cation, but very little K+. Cl- is the primary anion -Plasma: has a lot of proteins -Intersititual fluid: very little numbers of proteins Mnemonic to remember Na+ and Cl- concentration differences across cell membranes Cell [Na+] and [Cl-] are higher out of the cell than inside the cell Imagine a salt shaker sprinkling outside the cell
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