PUBHLTH 1 Lecture Notes - Lecture 64: Hypercholesterolemia, Immunodeficiency, Cardiovascular Disease

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7 Apr 2019
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Ask the who, where, and when questions to describe the epidemic by person, place, and time. Look for common source of exposure. Leading cause of death in u. s. Framingham study started in 1948. 1950/1952: lung cancer and tobacco smoking. Death rate from lung cancer 20x higher among smokers. And declined as the length of time increased since they had quit smoking. Cigarette smokers: 5x more to die from other cancers tongue, pharynx, larynx, esophagus as non-smoker. Heavy smokers (2 or more packs/day) were 2. 4x more likely to die from heart disease than non-smokers. 1920: heart disease leading cause of death in usa. 1948: first major epidemiologic study: framingham, massachusetts. 5000 healthy people, examined and data recorded: weight, bp, smoking habits, blood tests : 10 years: identification major risks factors: high bp, high blood cholesterol, smoking. July 3. 1981: rare cancer seen in 41 homosexuals (kaposi"s sarcoma)

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