PUBHLTH 1 Lecture Notes - Lecture 40: Hypercholesterolemia, Lung Cancer, Sarcoma
Document Summary
Heart disease leading cause of death in u. s. Lung cancer and smoking early 1950s. Questionnaire to physicians in uk: smokers, past smokers, non-smokers (age at starting to smoke, amount of tobacco smoked, when they had quit smoking ) Death rate from lung cancer 20x higher among smokers. Death rate among non-smokers was lower than of smokers. And declined as the length of time increased since they had quit smoking. Cigarette smokers: 5x more to die from other cancers tongue, pharynx, larynx, esophagus as non-smoker. Heavy smokers (2 or more packs/day) were 2. 4x more likely to die from heart disease than non-smokers. 1920: heart disease leading cause of death in usa. 1948: first major epidemiologic study: framingham, massachusetts. 5000 healthy people, examined and data recorded: weight, bp, smoking habits, blood tests . 10 years: identification major risks factors: high bp, high blood cholesterol, smoking. July 3. 1981: rare cancer seen in 41 homosexuals (kaposi"s sarcoma) disease.
