HSC 3537 Lecture Notes - Lecture 20: Isoniazid, Iatrogenesis, Antiarrhythmic Agent

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21 Jun 2016
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Introduction: drugs: medicines/substances used to prevent or treat a condition or disease, obtained from various sources: Molecular pharmacology (interaction of drugs and subcellular structures) Chemotherapy (drugs that destroy microorganisms, parasites, malignant cells) Toxicology (harmful effects of drugs and antidotes) Biological effects of drugs: pharmacodynamics: drug effects in the body, pharmacokinetics: calculation of drug concentration in tissues and blood over a period. Drug names, standards, and references: chemical name: exact chemical makeup, generic name: legal and scientific name, brand name: trademark of drug manufacturer. Food and drug administration (fda: united states pharmacopeia (usp, hospital formulary, physicians" desk reference (pdr ) Terminology of drug action: receptor: target of drug, action and interaction of drugs in the body: Combination of two drugs: additive action, antagonistic, synergistic, other actions of drugs. Drug toxicity: unwanted and potentially dangerous effects of drugs. Side effects (routine, often tolerable, reversible when drug is discontinued: contraindications (dangerous and ill-advised use, resistance (lack of beneficial response)

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