HSC 4555 Lecture Notes - Lecture 7: Tumor Suppressor Gene, S Phase, Myc
Document Summary
Definition: new growth that has occurred and will not stop growing. Cancer is the 2nd leading death in the u. s. Cancer manifests differently in each person because the genetic code is different in each individual. Cancer means crab (crabs do not let go) Benign grows more slowly mainly due to the low vascularity. Men are at more risk than women because their lifestyle is poor. Ex: not going to get a prostate exam. Women do more screening and testing than men. Overtime rates have fallen due to recognizing that for example smoking is bad for you. If the mutation is going to happen, it will happen cannot prevent this (unless you live in a bubble) P53 is a stoplight/tumor suppressor no longer is able to suppress the cell to stop replicating if p53 is damaged. These are the two other most important and widely studied genes in cancer. If p53 is not present unable to stop replication.