MCB 2004C Lecture Notes - Lecture 14: Missense Mutation, Diphtheria, Mutagen

28 views4 pages
21 Mar 2016
School
Department
Course
Professor

Document Summary

Mutant strain of salmonella to test if chemicals or food additives are a mutagen. If a back mutation occurs the chemical is a mutagen. Genetic exchange between two homologous dna sequences from two different sources. C. diphtheriae (gram-negative) normally does not make the diphtheria toxin. Gene needed (tox gene) comes from a phage. Bacteria + tox gene = toxigenic strain. The bacteria can become toxigenic due to lysogeny. Other bacteria that can become toxigenic due to lysogeny include: Strep. pyogenes, clostridium botulinum and v. cholerae. Dna transfer by phages that infect bacteria. Information taken from dead bacteria which releases it into environment. Artificially induced competence (when we do it in lab) Eukaryotic genes into easier to culture cells. Plasmid used to insert the gene into the cells. We can use bacteria to help clean the environment, have better food or make more antibiotics. Insertion of normal genes into cells to correct a specific genetic disorder.

Get access

Grade+20% off
$8 USD/m$10 USD/m
Billed $96 USD annually
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
40 Verified Answers
Class+
$8 USD/m
Billed $96 USD annually
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
30 Verified Answers

Related Documents