MCB 3020C Lecture Notes - Lecture 30: Neisseria, Human Microbiota, Glycocalyx

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Exposure and entry: portals of entry, adherence, invasion, colonization and growth, virulence factors produce damage (vl) Portals of entry: food and water bourne: vibrio cholera, salmonella, shigella (dysentery): often outbreaks in natural disasters causing sewage contamination of water. Food: clostridium botulinum, staphylococcus, & others: exhalation droplets: coughing & sneezing. Cat scratch fever: typically mild infectious disease caused by the bacterium. Bartonella henselae: parenteral (wound or puncture): penetration of skin or mucus membranes due to puncture. Animal bite deer tick-lyme"s disease: vector transmitted: Bubonic plague (yersinia pestis: microbe) rodent flea human. Between those 5 years, 25 million died of plague. Malaria: most microbes enter through breaks or wounds in skin or invasion of mucous membranes of respiratory, digestive, or genitourinary tract, mucous membranes: Respiratory track: microbes inhaled into nose or mouth in drops of moisture or dust particles (exhalation droplets) Gi track: food, water, and contaminated fingers (food & water bourne)

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