NUR 3145 Lecture Notes - Lecture 8: Esophagus, Esomeprazole, Nizatidine
Document Summary
Gi defenses, mucus, bicarbonate, blood flow, prostaglandins, gi invaders, h. pylori, nsaids, gastric acid, pepsin, smoking, number 1 cause of gastric ulcers. Plus: ppi or histamine2 receptor antagonist (h2ra) Ulcer, gerd, heartburn treatment: neutralize or buffer stomach acid, mom, aluminum hydroxide, calcium carbonate, sodium bicarbonate, blocks body"s signal to stomach to produce acid, cimetidine, ranitidine, famotidine, nizatidine, blocks secretion of acid into stomach, omeprazole, esomeprazole, lansoprazole, dexlansoprazole, rabeprazole, pantoprazole. Pharmacotherapy with antacids: antacids are alkaline substances that neutralize stomach acid to treat. Pud & symptoms of heartburn: types of antacids and their possible disadvantages. Histamine2-receptor antagonists (h2ra: suppress gastric acid secretion, cimetidine. Proton pump inhibitors (ppis: most effective for suppressing secretion of gastric acid, well-tolerated equally effective, omeprazole. [aciphex: take 30 min before 1st meal of the day, aes. [protonix] pantoprazole: ha, n/v/d (c. difficile infection risk), pneumonia, long-term use, fractures, hypomagnesemia, gastric cancer, interactions (reduce absorption/effects, some hiv/aids drugs, ketoconazole, itraconazole, clopidogrel.
