BMD RES 5HA Lecture Notes - Lecture 13: Pigment, Retina, Ommatidium
23 Feb 2017
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Building a road map: they"re not decoding the whole brain. Dpr"s: confirm the initial finding using a second approach, results may be false positive, make sure that experiment isn"t following the wrong proteins, find cells expressing the binding partners (ex. Dip"s: form pairs with dpr"s if i found that dpr"s are important proteins, then dip"s must be around to allow cells to associate, confirm that predicted cell pairs are really using dpr- Dip combinations to connect with each other: use deletion mutants, make specific antibodies, measure apoptosis, when cells don"t connect, the cells kill themselves; it"s better not to have those cells there because they"re not needed. The drosophila as a model system: the model organism: the fruit fly (drosophila melanogaster, molecular biologists usually only use fruit flies, morgan started studying the fruit fly in ~1908 at. It only takes 2 weeks to complete the cycle, making it very useful in experimental settings speeds up research.
