CH ENGR 104C Lecture Notes - Lecture 22: Heterocyclic Compound, Glycosidic Bond, Pyrimidine
7 Feb 2017
School
Department
Course
Professor
Document Summary
Miescher isolated nuclein from soiled bandages. Garrod studied rare genetic disorder: alkaptonuria; concluded that specific gene is associated with absence of a specific enzyme. Sumner purified urease; identified enzyme to be proteins. Griffith transforming principle a chemical transferred from dead bacteria to living cells caused genetically converted strains ( transformation ) Avery, mccarty, and macleod identified griffith"s transformation principle as dna. Watson and crick dna double helix. Three components make up a nucleotide: heterocyclic base either a pyrimidine or a purine. Heterocyclic molecule with at least one ring containing an atom other than carbon 2: pyrimidine aromatic organic compound with 2 nitrogens at c1 & c3 of a six- membered ring. Chem14c thinkbook. p. 101: pyrimidines in dna & rna, purine aromatic organic compound that consists of a pyrimidine ring and an imadazole ring (c3h4n2), purines in dna & rna, other common purines: Pyrimidine conformations are planar; purines are somewhat puckered.
