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Lecture 15

EE BIOL 185 Lecture 15: Cancer

3 Pages
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Department
Ecology and Evolutionary Biology
Course Code
EE BIOL 185
Professor
Pamela Yeh

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Description
Lec. Isa. Evolution Cancer Stats highest deaths for iyng lonnclus cr in others du Same decreasing leg mach) incrusind deaths of lung d bron chus cancer pts. in deCItong in wtorus t stomach Cancer an Evolutionary Pr challenge for murticell. Drganisms regs social cohesion /cooperation Gin Coordination of Cells by signals d check pts. ha detrmine when cells divide, die differcntiate Cancer Collaps of this Cooperation (le tumar suppression Oncogenes promote tumor (TS) gone Stop growth of damaged tf app priate growth mutated celts maintain Signals mutas in oncogenes induce. Wnutas, in TS gencs nuowly anwth of altered Cells to cancer cells NO LONUER being pitvint eg. Ras muta 00 Rm sitive stimulard1 Ceg muta in genes tlaat too Signal prigrammed cell death eg APC UTS gene n COIon can what (duses muta T spontaneous DR innorited env. .factor nfect iens RCA muting Sun reels div idly gen. x env. (GKE) virus f iness Cancer, Peto's paradox no correla, bin bedy t 1 canter Hwmans Micr both have NH01. chance of any cancer during lifctihe Whales humans MAN more. Cells f rtplicatinoy for Showld have T cancer rak -prob mers checkpt enRS to prevtnt ctrl d growth BUI DON'T human S nt copy f TP53 elephants -multiple copies 0 cm Thr. T risk of cancer Cmore for than humans dogs Twi. Trisk of cancer Criskuvis vff C certuin pt.) Cun Lec. Isa. Evolution Cancer Stats highest deaths for iyng lonnclus cr in others du Same decreasing leg mach) incrusind deaths of lung d bron chus cancer pts. in deCItong in wtorus t stomach Cancer an Evolutionary Pr challenge for murticell. Drganisms regs social cohesion /cooperation Gin Coordination of Cells by signals d check pts. ha detrmine when cells divide, die differcntiate Cancer Collaps of this Cooperation (le tumar suppression Oncogenes promote tumor (TS) gone Stop growth of damaged tf app priate growth mutated celts maintain Signals mutas in oncogenes induce. Wnutas, in TS gencs nuowly anwth of altered Cells to cancer cells NO LONUER being pitvint eg. Ras muta 00 Rm sitive stimulard1 Ceg muta in genes tlaat too Signal prigrammed cell death eg APC UTS gene n COIon can what (duses muta T spontaneous DR innorited env. .factor nfect iens RCA muting Sun reels div idly gen. x env. (GKE) virus f iness Cancer, Peto's paradox no correla, bin bedy t 1 canter Hwmans Micr both have NH01. chance of any cancer during lifctihe Whales humans MAN more. Cells f rtplicatinoy for Showld have T cancer rak -prob mers checkpt enRS to prevtnt ctrl d growth BUI DON'T human S nt copy f TP53 elephants -multiple copies 0 cm Thr. T risk of cancer Cmore for than humans dogs Twi. Trisk of cancer Criskuvis vff C certuin pt.) CunWhy are we vulnerable to cancer disease S10 W 2. Pathogens co-evoluc w/ host mismatch w mu env viruses line when sells multiply diH. Sun exposure, myml. of diff. Skin tones 11olerante to 5Mnlight incs cases their own fitness induce cancer more menstrual cycles igh
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