GE CLST 73B Lecture Notes - Lecture 9: Qwop, Dorsal Root Of Spinal Nerve, Neuroplasticity

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A pattern generator circuit: half center model. Cpg and neuronal control of left right alternation. Cpg is not a chip it"s a construct to explain why we can see construct that leads to locomotion Argue that it"s a smart cpg the spinal cord is well organized to produce patterns. Must coordinate appropriate discharge patterns between all motor pools. The cord has the ability (blackbox) to do the coordination. Dimitrijevic tried to get in the isolated spinal cord below the lesion. They"d give stimulus to jack up the excitability in the cord. They found that you can get a total rhythmic output and even limit to which side (left or right) Even though this cord has been damaged or cut you can produce isolation if given the chance. You"d have cut the dorsal root so no plastic info could come back. Adapt cpg output to 1) goals of animal and 2) constraints imposed by environment.

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