LIFESCI 2 Lecture 6: cell functioning & energy
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Department
Life Sciences
Course
LIFESCI 2
Professor
Arnold, A.P., Esdin, J.
Semester
Spring

Description
Lecture 6 4/14  Revision of epithelium cell: - Primary & secondary active transport both involved - 2 different proteins - primary: Na-K pump - secondary: Na-glucose cotransporter - if Na-K pump stops working glucose concentration in blood will decrease  cell-to-cell junctions - interaction between neighboring cells - 3 different types:  desmosomes  tight junctions  gap junctions - tight junction most important for function of cells  so that there’s tight control  prevent substance from moving in between cells  so that the cell can “supervise“ the substance entering & leaving  presence/absence of glucose in blood -> pancreas release different signaling molecules - insulin makes liver absorb glucose - glucagon makes liver release glucose - (antagonistic hormones)  activating G-protein coupled receptor 1. messenger activate receptor 2. G-protein activated 3. Alpha subunit goes to & activates adenylyl cyclase 4. Adenylyl cyclase converts ATP -> cyclic Amp (second messenger) 5. Second messenger activates prote
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