LIFESCI 7C Lecture Notes - Lecture 2: Intermediate Filament, Cell Adhesion, Dynein

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Requires: (1) molecular mechanisms for adhesion (2) specialized structures for communication (3) tissue differentiation. Intermediate filaments stable components of the cytoskeleton, they have a central conserved domain, terminal ends that are highly variable, and they play a structural or stress bearing role in cells. Movement: cilia and flagella structure- central microtubules and dynein arms (motor proteins) flagella present in bacteria and eukaryotes but they are different. Tissues- epithelial, connective, muscle, and nervous combine to make up organs. Binds many cells into tissues and allows them to be ogans. 3 ways to stick together: extracellular matrix, cytoskeleton. Adherens junction- extend across 2 cell membranes, fibrous network, connects cytoskeletons of all of the cells in the epithelial layer connected to the microfilaments. Desmosomes- common is tissues that stretch, cadherins connected to intermediate filaments in the cytoplasm.

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