MCD BIO 90 Lecture Notes - Lecture 1: Viral Vector, Myc, Oncogene
DepartmentMolecular, Cell, and Developmental Biology
Course CodeMCD BIO 90
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Thursday, October 10, 2019
•Look the same, potency, colony, functions, result of manipulation!
-Source is limited, from the blastocyst, ICM!
-Younger, no epigenetic memory!
-Controversy, ethical concerns!
-Personalized — reduce the chance of rejection!
-Epigenetic memory — reprogramming is imperfect and ineﬃcient, the cells
are more likely to reverse to the previous cell !
-Any adult cells !
-c-Myc is related to cancer —oncogenes — you have to make sure that is
shut oﬀ and suppressed after!
-Viral vectors — break the genome — introduce proteins, or not permanently
changing the genome
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