SOC GEN 5 Lecture Notes - Lecture 10: Endocrine Disruptor, Antiseptic, Endocrine System
25 Apr 2020
School
Department
Course
Professor
Document Summary
Hormone: class of signaling molecules that are transported by circulator system to table distant organs. Endocrine system: collection of glands of an organism that carries hormones to circulatory system. Disruptors interfere with body"s endocrine system function -- increasing/decreasing normalizing hormone levels, act as hormone or block response to hormone. *if it interferes at any step/level quali es as ed carried through blood to distant organs. Bc hormones are messengers interconnected systems and feedback loop of exchanges. Major classes of hormones steroidal lipophilic easily crosses membrane, doesn"t need receptors nonsteroidal water soluble amine, petide, protein needs receptors transfer signal. 87 thousand known chemical substances in commercial use in us most haven"t been tested. Scienti c problem high exposure lose dose e ects exposure early in life dramatic consequences. "dose makes the poison" u-shaped trend for exposure and e ect forefather of antisepsis.
