BIOL 3402 Lecture Notes - Lecture 4: Lymphatic Vessel, Natural Killer Cell, Antimicrobial Peptides

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5 Oct 2016
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Organs of immune system: tonisls/adenoids, lymph nodes, lymp vessels, thymus, spleen, appendix, peyer"s patches, bone marrow. Immune system: not an organ system, but a cell population that inhabits all organs and defends the body from agents and disease: lymphatic system. Pathogens: agents capable of producing disease: virus, bacteria, fungi. 3 lines of defense: 1) skin & mucus membranes (barrier, 2) non-specific killers (innate) (eater cells) Leukocytes & macrophages: 3) specific immunity (learned) (smart cells) 1st line: physical barrier: limits access to internal tissues, not true immune response, no recognition of foreign objects, physical: skin, mucus, saliva, tears (flushing, chemical: tears (lysosome), stomach acid, gut bacteria, skin: toughness of keratin. Summary of main physical and chemical barriers: sebaceous glands, tears, wax, mucus, saliva, cilia, low ph, sweat, stomach acid, intestinal enzymes, defecation, urination, intact skin. Immunology: study of body"s response to infectious agents.

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