BIOL 3402 Lecture Notes - Lecture 12: Phantom Pain, Neuroglia, Electrophysiology
Document Summary
Regain control of area: more axonal branches. Ends roll up neuroma = phantom pain. If soma is intact (grows big while healing) Some neurilemmal remains: by 6 months there is some improvement, by 2 years you"re either healed or not. Protein secreted by a gland, muscle, or glial cells and picked up by the axon terminals of neurons: prevents apoptosis = programmed cell death. Study of cellular mechanisms for producing electrical potentials and currents. Chemical gradients across cell: inside cell = negative (k, outside cell = positive (na) Current = flow of charged particles: ions like k and na, gated channels. Plasma membrane more permeable to k: steeper concentration gradient, na-k pump maintains. Cytoplasmic anions cannot escape due to charge or size. Alters permeability of membrane: by opening or closing ion channels. Changes in membrane potential: be the dendrite/soma. Chemical stimulant (ligand: binds to gated channel to open for sodium to enter, positive ions raise membrane potential (depolarization)
