BIOL 1107 Lecture Notes - Lecture 15: Ubiquitin, Tata-Binding Protein, Transgenerational Epigenetic Inheritance
Document Summary
How eukaryotes control gene expression many different ways. * then exploring: regulation via chromatin remodeling, regulation during transcription initiation, regulation following transcription. Introduction to control of gene expression in eukaryotes. The regulation of gene expression is more complex in eukaryotes than in prokaryotes. Forms the multicellular society we call an individual. Eukaryotes can control gene expression at levels of. Eukaryotes have three additional levels of control: Rna processing to produce a mature mrna. In eukaryotes, dna is wrapped around proteins to create a structure called chromatin. Rna polymerase cannot access the dna when it is tightly coiled. Chromatin remodeling must unpack the dna at particular genes so they can be transcribed. Chromatin has a regular structure with several layers of organization. Dna is wrapped around histones and other proteins. About 200 bases of negatively charged dna wrap around a core of 8 positively charged histone proteins. Repeating, beadlike structures spaced with linker dna.
