BIOL 1108 Lecture Notes - Lecture 1: Electrophoresis, Genetic Drift, Natural Selection

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7 May 2018
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Evolution: Chapter 1
Core Concepts
• Genetic variation refers to differences in DNA
sequences.
• Patterns of genetic variation can be described by allele
frequencies.
• Evolution is a change in the frequency of alleles or
genotypes over time.
• Natural selection leads to adaptations, which enhance
the fit between an organism and its environment.
• Migration, mutation, genetic drift, and non-random
mating are nonadaptive mechanisms of evolution.
• Molecular evolution is a change in DNA or amino acid
sequences over time.
Genetic variation: fruit flies are much more variable in
genetic make-up than humans (10X more) and
penguins (5X more)!
What can cause genetic variation?
A mutation…
– Somatic
– Germ-line
and they can be:
– Deleterious
– Neutral
– Advantageous
then recombination gives
new combinations not
present in parent
population
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