MCB 2000 Lecture Notes - Lecture 17: Glyceraldehyde, Isomerization, Dihydroxyacetone Phosphate
Document Summary
Atp levels are maintained in equilibrium by adenylate kinase. Consequence: small net change in atp results in large change in amp. Amp thus becomes a signal for a low energy state. Synthesis of atp is as needed, coordinated with cellular needs for atp. Change in [atp] drastically changes [adp] and [amp] (50%), signi cant. Energy status can be indicated by energy charge. Energy charge = ([atp] + 0. 5[adp])/([atp] + [adp] + [amp]) Change rates depending on how much energy is needed. Glycolysis: occurs in the cytoplasm, happens all the time but the rates change. !1: investment phase (input atp) vs recovery of atp with net 2 molecules of atp. Wednesday, march 22, 2017: 10 reactions, atp invested v atp generated/nadh generated, generate atp in 2 steps. Glucose (6c) + 2adp + 2pi + 2nad+ -(10 reactions)> 2 pyruvate + 2tp (net) + Glucose oxidized to pyruvate (loss of electrons) Nad+ reduced to nadh (gain of electrons)
