MCB 2410 Lecture Notes - Lecture 1: Mendelian Inheritance, Deoxyribose, Autosome

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Genetics - the study of heredity and the variation of inherited characteristics. All organisms use common genetic systems, unifying biology. Genome is made of deoxyribose nucleic acid (dna) Composed of 4 bases - a,t, c, g. Mutations in dna can create changes in phenotype. Understand the sequences and you can maybe change them in a beneficial way. Two copies if the game gene, one from mother and the other from father, make up a pair of chromosomes. Allele - different variations of a gene. Central dogma says : dna is replicated, transcription, translation, protein synthesis. Can provide gene therapy for human diseases. A technique to create targeting mutations in dna. Two types of cells (prokaryotes and eukaryotes) Chromosomes are made up of nucleic acids and proteins. Genes are found in multiple variations (alleles) are located on chromosomes. Mutations in dna can create changes in phenotype that can be passed from parents to offspring. Genetic information transferred from dna rna protein.

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