MCB 2210 Lecture Notes - Lecture 29: Telomerase, Tandemly Arrayed Genes, Telomere

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Necrosis- refers to premature death due to infection or injury, elicits an immune response. Apoptosis- is a form of programmed cell death (cell suicide), this process is sometimes influenced by an intracellular degradation mechanism termed autophagy (self-eating) Phagocytosis- involves one cell (a phagocyte like microphage) eating a dying cell such as an apoptotic or infected cell. Apoptosis is crucial for normal development: benefits of apoptosis: Eliminating abnormal cells during development in a quality control process. Elimination of cells that could be dangerous to the organism such as self-reactive immune cells. Elimination of cells with the potential to cause cancer, including those with damaged dna. The killing of virus-infected cells by cytotoxic t-lymphocytes. Apoptosis can be triggered by intrinsic or extrinsic pathways. Bcl2 family of proteins: cytochrome then binds and activates apaf1- multiple apaf1"s will form a structure called the apoptosome where caspases gather.

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