MCB 2410 Lecture Notes - Lecture 21: Karyotype, Gene Duplication, Synteny

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Biological evolution: genetic change in a group of organisms, 2 step processes, genetic variation arises increase and/or decrease in frequencies of genetic variants, evolution: change in allele frequencies within a population over time. Evolutionary forces change allele frequencies: mutation, migration, genetic drift, natural selection, differential reproduction of genotypes, allows populations to become better suited to their environments trait that provides reproductive advantage increases frequency in population. Two types of evolutionary change: cladogenesis, evolution that causes one lineage to split into two, more clear-cut division, anagenesis, evolution within a lineage. Populations have lots of genetic variation: neutral-mutation hypothesis, many molecular variations are adaptively neutral, e. g. hair color. Dna sequence variation: dna sequence similarities can be used to assess genetic relationships. Modes of speciation: sympatric speciation: speciation without any geographic barrier, e. g. insects evolving to utilize different resources, apple maggot fly, speciation through polyploidy. Genome evolution: karyotype rearrangement can lead to new species.

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