NURS 3110 Lecture Notes - Lecture 15: Viral Hepatitis, Hdv, Blood Transfusion
Document Summary
There are 4 types of fungal infections: systemic cutaneous, subcutaneous, and superficial. Need to develop a drug that works only on microbe not on normal cells. Azoles = always liver (concern about drugs that metabolize in liver) Among the smallest of all life forms. Nucleic acid packaged in protein coat (capsid) that is composed of multiple, nearly identical repeating protein subunits (capsomeres) The viral capsid has 2 types of symmetry: naked or helical. Helical - a coil of protein subunits along the helical spiral of the viral nucleid (found in rna only) The icosahedron is the basic design of the geodesic dome. It is the most efficient symmetrical arrangement that linear subunits can take to form a shell with maximum internal capacity. Nucleocapsid may be surrounded by a lipid envelope acquired as the virus buds from the host cell membranes. Viral encoded proteins are inserted into this lipid bilayer, i. e. the hemagglutinin [h] and neuraminidase [n] in influenza.
