PNB 2250 Lecture Notes - Lecture 33: Ascl1, Symmetry In Biology, Mesoglea

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Week 13 lecture 33 evolution of invertebrate nervous systems. General points about nervous systems: as animals become more complex, the interactions between neurons and other neurons and cells become more complex. Formation of a brain and spinal cord: e(cid:448)e(cid:374) though o(cid:374) a (cid:272)ellular (cid:271)asis, (cid:374)euro(cid:374)s do(cid:374)"t (cid:272)ha(cid:374)ge (cid:373)u(cid:272)h, ho(cid:449) they are arra(cid:374)ged a(cid:374)d interact with other cells changes dramatically. Is responsible for emergent properties of thought: no visible neurons. No neuronal cells: no synapses, possess the same genes needed for functional neurons. Ascl1: possess potential to form neurons, waves of calcium pass through cells. Cnidarians: coral, jellyfish, etc, first evidence of a nervous system, neurons are multifunctional. Inter: peptide nts, neurons form a connecting network (mesoglea, network controls contractile cells. Allow for the direct control of muscle contraction. First evidence for use of a nervous system to collect environmental info. Flatworms: first evidence of bilateral symmetry. Mirror image of right and left sides.

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