PNB 2264 Lecture Notes - Lecture 1: Metacarpal Bones, Hamstring, Patellar Ligament
25 Feb 2017
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Take quizzes on huskyct for extra credit. The human organism: anatomy is structure, physiology is function. Structure and function are related; structure is adapted to function. 3 major organizing principles: hierarchical organization (structure/function relationship) Structure is adapted to function: homeostasis. Not an equilibrium, rather a dynamic steady state (dynamic constancy), especially of the ecf. Within narrow limits - may be small uctuations around a set point . Set point is a determined average over a long period of time: cell-to-cell communication. To coordinate re exes and local homeostatic responses, cells must be able to communicate with one another (hormones, nerve cells, paracrine, autocrine substances) Body fluid compartments: intracellular uid (inside) - 67, extracellular uid (ecf): Tb decreases shiver, tb increases, back toward normal or set point. Negative feedback in this case because response removed stimulus. If: stimulus -> increases response, response increases which enhances stimulus change, positive feedback.
