PNB 2265 Lecture Notes - Lecture 9: Pacemaker Potential, Qt Interval, Muscarinic Acetylcholine Receptor

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Clinical Uses of EKG
AV block: no coordination of contractility (no/reduced QRS)
Some can depolarize atria even if AV nodes not working
Because purkinje fibers also have pacemakers
Difference is speed
No coordination between atria and ventricle
Long QT syndrome: slow recovery from contraction
May lead to VFIB
QT interval = start of depolarization to end of T
T wave is ventricular repolarization
Mediation by potassium channel influx
Fibrillation: NOT tachycardia
Uncoordinated electrical activity of atria and ventricles
Afib = atrial
Ventricular = ventricle
Pockets of depolarization = never gets added together
Heart cannot pump!
Defibrillator = all in refractory period so can be together again
Myocardial Infarction
Heart attack
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