BIPN 100 Lecture Notes - Lecture 5: Vesicle Fusion, Phospholipid, Axon Terminal
16 Dec 2018
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Document Summary
Know the content of the lecture slides, know that when one aspect of a system is changed, how other aspects of the system will be. Propagation of action potentials: propagate: to spread and promote widely, action potential is initiated at the trigger zone. Initiates at one spot: depolarization occurs first at the closer electrodes, depolarization can go in both directions, but in reality, as the ap propagates, the section behind the active region will be in refractory. Caspr: a protein that serves as a paranodal junction between the myelinating glial cell and the axon, helps the myelin stay in place on the axon. If it can"t propagate anymore, you can"t move your muscle: prevents aps from propagating (going down the axon) and you will be unable to release neurotransmitters. Which region of a myelinated axon has the highest density of voltage-gated ion channels: nodes of ranvier.
