BILD 2 Lecture Notes - Lecture 11: Systolic Geometry, Pulmonary Vein, Heart Valve
21 Mar 2018
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Stimulus: glucose and parasympathetic system: allows uptake of glucose -> glucose metabolism. Inserts transporters in the membrane: causes anabolism. Synthesizing glycogen: polymers of glucose to be stored, muscles and liver are the storage site of glucose, muscles do not release the glycogen they synthesize. Liver breaks down the glycogen and releases glucose to the body. Insulin makes you fat: glucagon - "fasted state, breaks down glycogen to increase free glucose levels. Large amounts of glucose leaving the system is followed by large amounts of water due to osmolarity gradient: 2 subtypes of diabetes mellitus, type i diabetes. Lack of insulin due to malfunctioning beta cells in pancreas: usually due to autoimmune disease, these patients are insulin dependent, usually appeared in babies/adolescents. Strongly associated with overweight/obesity: adipocytes (fat tissue) release hormones that cause insulin resistance, circulatory system, pressure. "adult diabetes: pressure = volume of contents/volume of container. Increase volume of contents (increase amount of blood) increases pressure.
