BIMM 110 Lecture Notes - Lecture 8: New Idea, Cas9, Wild Type
25 Feb 2017
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This is a way to change dna precisely: nhej (non-homo end joining, error prone mech that often generates deletions or insertions, thus disabling genes. Malaria: history, first described in the early egyptian and greek literature from. Malaria: global impact: according to the who world malaria report (who, 2014), ~3. 4 billion people are at risk of being infected with malaria each year according to the centers for. Malaria: the pathogen and the vector: pathogen: single cell parasite from the genus plasmodium, infects red blood cells and causes them to burst, vector (transmitted by): mosquitoes (genus anopheles) More red blood cells (rbcs) are infected: chills, fever, aches, insufficient supply of oxygen, sexual forms of the parasite are taken up by blood-sucking mosquitoes, continuing the life cycle. Developing a gene therapy to stop malaria spread in mosquito. Step 1: a mosquito gene was discovered that was activated by blood meal: agcp promoter: activated by blood meal.
